Dating of multidose vials


30-Aug-2017 11:31

The name of the medication, ward, labeling of the vials, the date of opening, and storing temperature were recorded for each vial.

Remained contents of each vial were cultured using appropriate bacterial and fungal growth media.

However, some doctors may have instructed their patients to use a preservative-free vial more than one time.

These physicians may be concerned that the patient is allergic to preservatives or that the patient may experience an adverse effect from the preservative.

An unopened vial may be retained for use until the date indicated on the label if properly stored.

It is of utmost importance that the medication vial and the materials used for withdrawing and injecting the medication are sterile before use and that all precautions are taken to ensure that the medication and the materials are not contaminated during the procedure.

For multiple dose vials (vials that contain an antimicrobial preservative) the USP states that the effectiveness of antimicrobial preservatives cannot be ensured beyond 28 days following initial penetration of the stopper, unless specified otherwise by the manufacturer.

In general, you should date the vial upon initial penetration of the stopper, store the vial in the refrigerator, and discard it 28 days later.

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It is essential that you use proper aseptic technique throughout the process of administering an injection regardless whether the vial is preservative-free or contains a preservative.When you have removed the needle from the vial, carefully recap the needle with the plastic cover without injuring yourself.Allowing the dose of medication to come to room temperature may help to reduce discomfort during administration.Wipe the injection site on your skin well with a new sterile alcohol pad. Remove the plastic cover from the end of the needle and inject the medication in the manner you were shown in the physician’s office.

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When the entire dose has been injected, remove the needle from the skin and place the entire syringe/needle assembly into the sharps container for used needles and syringes."Multiple Dose Vials" are intended to be used more than once.



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